Emmanuel Skordalakes
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Emmanuel Skordalakes

Protein clamps tight to telomeres to help prevent aging and ...

"Cdc13 has a crucial support role in maintaining and lengthening telomeres, which are reduced in length through every round of DNA replication," said Emmanuel Skordalakes, Ph.D., assistant professor in Wistar's Gene Expression and Regulation Program and senior author of the study. "We ...

Aging: Scientists further unravel telomere biology

In a study published in the journal Structure, available online now, a team of scientists led by Emmanuel Skordalakes, Ph.D., an associate professor in The Wistar Institute Cancer Center's Gene Expression and Regulation Program, has determined how mutations in a particular region of ...

Exercise Guards White Blood Cells Against Aging

Telomeres can be thought of as the plastic tips on the end of shoelaces, which prevent the lace from fraying, explained Emmanuel Skordalakes, an assistant professor of gene expression and regulation at The Wistar Institute in Philadelphia. Over the life span, cells continue to divide. ...

Discovery of Protein 'motif' crucial to telomerase activity offers insight in the hunt for drugs to...

"Telomerase is a unique protein-RNA complex where the protein subunit uses its RNA component as a template to add identical fragments of DNA to the end of chromosomes," said Emmanuel Skordalakes, Ph.D., associate professor in the Gene Expression and Regulation program of Wistar's ...

Fit People Release More Fat-Burning Molecules During Exercise ...

Abundant research has shown that exercise is beneficial to health, from reducing the risk of heart disease, stroke and type 2 diabetes, to prolonging life, said Emmanuel Skordalakes, an assistant professor in the Gene Expression and Regulation Program at the Wistar Institute in ...

It takes two to tangle: Scientists further unravel telomere ...

In a study published in the journal Structure, available online now, a team of scientists led by Emmanuel Skordalakes, Ph.D., an associate professor in The Wistar Institute Cancer Center's Gene Expression and Regulation Program, has determined how mutations in a particular region of ...

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